This common food additive causes leaky blood vessels, can trigger cancer to spread faster: Study

More disturbing findings about the commonly used food additive “titanium dioxide” have just been released.  A recent scientific study found that this nanoparticle causes blood vessels to enlarge and leak and that these leaky blood vessels can trigger existing cancerous tumors to grow faster and to spread to new areas of the body.

titanium dioxid effect on blood vessels-before and after

We have been reporting on troublesome research findings surrounding the food additive nanoparticle ‘titanium dioxide’  for a number of years now.  Some studies have found that this food additive can cause gaps in the lining of intestinal walls to widen, causing leaking which can exacerbate intestinal disorders like colitis and Crohn’s Disease to worsen (a, b, c).

titanium dioxide effect on intestines before and after shots

titanium dioxide worsens colitis

In this latest study researchers from the National University of Singapore found that the food additive titanium dioxide (as well as other nanoparticles) which are commonly used in U.S. processed foods, personal care products and medicines, may have unintended and harmful side effects.  More specifically, the researchers found that:

, which are designed to kill , may accelerate metastasis. Using as a model, they discovered that common nanoparticles made from gold, , silver and silicon dioxide – and also used in nanomedicines – widen the gap between blood vessel cells, making it easier for other cells, such as cells, to go in and out of “leaky” blood vessels.

The phenomenon, named ‘nanomaterials induced endothelial leakiness’ (NanoEL) by the NUS team,

accelerates the movement of cancer cells from the primary tumor and also causes circulating cancer cells to escape from blood circulation. This results in faster establishment of a bigger secondary tumor site and initiates new secondary sites previously not accessible to cancer cells.

But you don’t need to ingest nanoparticles like titanium dioxide in medicine to have a negative impact…

“For a , the direct implication of our findings is that , pre-existing exposure to nanoparticles – for instance, through everyday products or environmental pollutants – may accelerate cancer progression, even when nanomedicine is not administered.
-Dr. David Leong, research co-leader and Associate Professor, Department of Chemical and Biomolecular Engineering at NUS Faculty of Engineering
SourceNanoparticles may promote cancer metastasis

Journal Reference: Fei Peng et al. Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness, Nature Nanotechnology (2019). DOI: 10.1038/s41565-018-0356-z

Where is the food additive nanoparticle Titanium Dioxide hiding, and what adverse effects have been linked to it in scientific and medical studies?

The following excerpted material is from our book,

“The Food Hackers Handbook”:  Food Hacker BOOKCOVER-CFL

Titanium Dioxide

Where Found

This additive is present in processed foods containing nanoparticles common on grocery shelves, and in fast food and conventional restaurant foods. Frequently unlabeled in U.S. foods (though nanoparticles are required to be labeled in EU
countries) this additive is used as a white pigment food coloring for processed foods such as skim milk, white cheese, yogurt, frosting/frosted foods, icing, candies, snack foods, mayonnaise, salad dressings, powdered sugar, marshmallows, pudding, breakfast toaster pastries, and non-diary coffee creamer, among many others. It is also commonly used in U.S. medicines and toothpaste.


Red Flags

Scientists are still determining the health safety and potential health hazards of nanoparticles in food. According to the professional organization American Society of Safety Engineers, ingested nanoparticles can be absorbed through small nodules in intestinal tissue (Peyer’s Plaques) that are part of the immune defense system. If nanoparticles enter the digestive system and proceed into the bloodstream, they can potentially move throughout the body and cause damage. Additionally, “Nanoparticles may also accumulate in certain organs, disrupt and impair biological, structural and metabolic processes and weaken the immune system.” Animals studies have demonstrated that nanoparticle ingestion changes the structure of the lining of the intestinal walls. Among other potential problems, such structural changes hold the potential for over-absorption of harmful compounds. Additionally, research has indicated there are potential adverse health effects of nanoparticles on respiratory and cardiovascular systems, and studies of manufactured nanoparticles have demonstrated toxic properties. Among other health-related issues researchers are studying the potential link between Titanium Dioxide nanoparticles in food and an increased risk for inflammatory bowel diseases such as Crohn’s disease and colitis.