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BPA Exposure in Pregnancy may Adversely Affect Unborn Babies, say Scientists
There have now been thousands of novel and replication studies linking adverse health effects to the endocrine-disrupting food chemical BPA. In this latest study scientists warn that exposure to this food chemical during pregnancy has the potential to alter offspring’s gut bacteria levels, thereby adversely affecting the health and well-being of the unborn child.
A chemical called bisphenol A — BPA — used in plastic packaging and in the linings of food and beverage cans, may be passed from a mother to her offspring during pregnancy and cause changes in the gut bacteria of the offspring, according to an international team of researchers.
In animal studies researchers observed that exposure to BPA during pregnancy caused chronic inflammation in the offspring’s intestines and liver. The researchers also notedsigns of increased gut permeability — or leaky gut — and a decrease in the diversity of gut bacteria and anti-inflammatory bacterial metabolites, such as short-chain fatty acids…Leaky gut and decreased gut-bacteria diversity and metabolites are considered biomarkers — or indicators — of inflammation-related chronic diseases…
The offspring were not directly exposed to BPA, but received exposure to the chemical from their mother through the placenta and in the milk. This exposure may lead to long-lasting health problems…
Journal Reference: Lavanya Reddivari, D. N. Rao Veeramachaneni, William A. Walters, Catherine Lozupone, Jennifer Palmer, M. K. Kurundu Hewage, Rohil Bhatnagar, Amnon Amir, Mary J. Kennett, Rob Knight, Jairam K. P. Vanamala. Perinatal Bisphenol A Exposure Induces Chronic Inflammation in Rabbit Offspring via Modulation of Gut Bacteria and Their Metabolites. mSystems, 2017; 2 (5): e00093-17 DOI: 10.1128/mSystems.00093-17